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- Moreover, a component of endothelial dysfunction has been proposed, which may contribute to irregular vessel reactivity.
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- Effects of testosterone on coronary vasomotor regulation in men with coronary coronary heart illness.
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However, testosterone in physiologic doses may even be useful in patients with angina , have greater ischemic thresholds and improved high quality of life . Short-term intracoronary administration of testosterone induces coronary artery dilation and increases coronary blood circulate in men with established coronary artery disease . Therefore, an interaction of endogenous elements of the patient’s danger profile as nicely as the testosterone dosing could also be problems with whether antagonistic events occur. Erythrocytosis has been reported as a possible effect of testosterone, which can be beneficial in sufferers with anemia. The best risk of erythrocytosis occurs with injectable forms of testosterone in contrast with transdermal preparations, particularly in supraphysiologic doses. An enhance of up to 44% of the baseline hematocrit has been reported .
Moreover, testosterone has been used within the treatment of lowered muscle mass and bone density as properly as anemia. The role testosterone may play in the growth of cardiovascular disease has more and more become the subject of present curiosity . Anabolic androgenic steroid use has elevated over the past decade, despite its potential for opposed effects. They continue to be used by Olympic stage athletes, and have even unfold to high school stage athletes, noncompetitive bodybuilders and leisure athletes (Sullivan et al 1998; Dhar et al 2007).
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